{"id":11698,"date":"2025-10-18T14:03:22","date_gmt":"2025-10-18T12:03:22","guid":{"rendered":"https:\/\/fermi.univ-tlse3.fr\/?post_type=tribe_events&#038;p=11698"},"modified":"2025-11-12T09:48:01","modified_gmt":"2025-11-12T08:48:01","slug":"tba-ashok-prasad-lpt-seminar-25-11-2025-14h","status":"publish","type":"tribe_events","link":"https:\/\/fermi.univ-tlse3.fr\/fr\/home\/event\/tba-ashok-prasad-lpt-seminar-25-11-2025-14h\/","title":{"rendered":"La morphologie comme lecture de l\u2019\u00e9tat cellulaire : classification, m\u00e9triques et dynamiques. &#8211; (Ashok Prasad \/ LPT \/ Seminar). &#8211; 25\/11\/2025, 14H"},"content":{"rendered":"<p><span style=\"font-size: 20px; background-color: #f18500;\">S\u00e9minaire LPT<\/span><\/p>\n<p><span style=\"font-size: 20px;\"><span style=\"color: #191970;\"><strong>Ashok Prasad <\/strong><\/span>(Universit\u00e9 d\u2019\u00c9tat du Colorado)<\/span><\/p>\n<p><span style=\"background-color: #cecece;\">Seminar LPT, 25\/11\/2025, 14H, 3R4, salle de conf\u00e9rence<\/span><\/p>\n<p><span style=\"font-size: 20px;\"><span style=\"color: #191970;\"><strong>Summary<\/strong><\/span><\/span><br \/>\nCell morphology offers a powerful and underutilized lens for understanding cellular identity, behavior, and state. While transcriptomic and proteomic profiling have revolutionized our capacity to characterize cells, quantitative morphological features can provide complementary insights into cell state and function. In this talk, I will present our recent work demonstrating that cells can be robustly classified using a range of morphological metrics derived from microscopy images. I will discuss our ongoing efforts for deeper insight. These include studying the relationship between cell shape, actin structure and nuclear size and shape as well as by developing new morphological measures that are sensitive to the structure and dynamics of intracellular structures, especially the actin cytoskeleton and other dynamic biopolymer networks. We simulate the actin cytoskeleton, incorporating the action of molecular motors and cross-linkers, and look for features that are sensitive to different initial conditions and differences in temporal dynamics. Ultimately, we seek to build a framework in which cellular morphology is treated as a high-dimensional, information-rich signature of cell state. Our work is part of a broader vision of morphology-based phenotyping as a bridge between structure and function in living systems.<\/p>\n<hr>\n<div class=\"leaflet-map WPLeafletMap\" style=\"height:300px; width:70%;\"><\/div><script>\nwindow.WPLeafletMapPlugin = window.WPLeafletMapPlugin || [];\nwindow.WPLeafletMapPlugin.push(function WPLeafletMapShortcode() {\/*<script>*\/\nvar baseUrl = atob('aHR0cHM6Ly97c30udGlsZS5vcGVuc3RyZWV0bWFwLm9yZy97en0ve3h9L3t5fS5wbmc=');\nvar base = (!baseUrl && window.MQ) ?\n    window.MQ.mapLayer() : L.tileLayer(baseUrl,\n        L.Util.extend({}, {\n            detectRetina: 0,\n        },\n        {\"subdomains\":\"abc\",\"noWrap\":false,\"maxZoom\":18}        )\n    );\n    var options = L.Util.extend({}, {\n        layers: [base],\n        attributionControl: false\n    },\n    {\"zoomControl\":true,\"scrollWheelZoom\":true,\"doubleClickZoom\":true,\"fitBounds\":true,\"minZoom\":9,\"maxZoom\":18,\"maxBounds\":null,\"attribution\":\"<a href=\\\"http:\\\/\\\/leafletjs.com\\\" title=\\\"Une biblioth\\u00e8que JS pour des cartes interactives\\\">Leaflet<\\\/a>; \\u00a9 <a href=\\\"http:\\\/\\\/www.openstreetmap.org\\\/copyright\\\">OpenStreetMap<\\\/a> contributeurs\"},\n    {});\nwindow.WPLeafletMapPlugin.createMap(options).setView([43.560830727361,1.4672373725804],16);window.WPLeafletMapPlugin.createScale({});});<\/script>\n<script>\nwindow.WPLeafletMapPlugin = window.WPLeafletMapPlugin || [];\nwindow.WPLeafletMapPlugin.push(function WPLeafletMarkerShortcode() {\/*<script>*\/\nvar map = window.WPLeafletMapPlugin.getCurrentMap();\nvar group = window.WPLeafletMapPlugin.getCurrentGroup();\nvar marker_options = window.WPLeafletMapPlugin.getIconOptions({});\nvar marker = L.marker(\n    [0,0],\n    marker_options\n);\nvar is_image = map.is_image_map;\n    marker.setLatLng( map.getCenter() );\nif (marker_options.draggable) {\n    marker.on('dragend', function () {\n        var latlng = this.getLatLng();\n        var lat = latlng.lat;\n        var lng = latlng.lng;\n        if (is_image) {\n            console.log('leaflet-marker y=' + lat + ' x=' + lng);\n        } else {\n            console.log('leaflet-marker lat=' + lat + ' lng=' + lng);\n        }\n    });\n}\nmarker.addTo( group );\nmarker.bindPopup(window.WPLeafletMapPlugin.unescape('Salle de conf\u00e9rence (- B\u00e2timent 3R4)'));window.WPLeafletMapPlugin.markers.push( marker );\n        });<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Lieu : Salle de conf\u00e9rence, B\u00e2timent 3R4<\/p>\n","protected":false},"author":5,"featured_media":0,"template":"","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","neve_meta_reading_time":"","_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[],"tribe_events_cat":[48,313,233],"class_list":["post-11698","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-events","tribe_events_cat-lpt","tribe_events_cat-seminars","cat_events","cat_lpt","cat_seminars"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - 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