{"id":8031,"date":"2022-04-11T06:30:44","date_gmt":"2022-04-11T04:30:44","guid":{"rendered":"https:\/\/fermi.univ-tlse3.fr\/?post_type=tribe_events&p=8031"},"modified":"2022-04-11T08:47:52","modified_gmt":"2022-04-11T06:47:52","slug":"reconfigurable-self-assembly-evolutive-dna-nanomachines-coffee-ring-diagnostics-and-living-crystals-damien-baigl-lpco-seminar-14-04-14h","status":"publish","type":"tribe_events","link":"https:\/\/fermi.univ-tlse3.fr\/fr\/home\/event\/reconfigurable-self-assembly-evolutive-dna-nanomachines-coffee-ring-diagnostics-and-living-crystals-damien-baigl-lpco-seminar-14-04-14h\/","title":{"rendered":"Reconfigurable self-assembly: evolutive DNA nanomachines, coffee-ring diagnostics and living crystals (Damien Baigl \/ LPCNO \/ Seminar). – 14\/04, 14H"},"content":{"rendered":"

Damien Baigl<\/strong> (ENS Paris)<\/p>\n

Abstract :<\/strong><\/p>\n

Self-assembly is a both a formidable method to organize molecular or colloidal entities into functional superstructures and a playground for the scientific endeavor on how matter organizes itself. Self-assembly is also a key-feature of how life builds its components. However, compared to their living counterparts, synthetic materials made by self-assembly usually lack some of the characteristic properties of living systems such as reconfigurability, adaptability or evolution. In this presentation, I will describe different systems where such properties can emerge from self-assembled synthetic materials. First, I will show that elaborate user-defined DNA nanostructures (e.g., DNA origamis, tiles, extended nanogrids) can be obtained by spontaneous self-assembly at room temperature for the first time with a unique capability to adapt to their environment by changing their shape, transforming and evolving [1,2]. Then, I will present a new DNA self-assembly principle that does not rely on base-pairing principles. I will show in particular that photosensitive DNA intercalating molecules can co-assemble with DNA bases to form new extended supramolecular materials of unprecedented properties. I will describe in particular the formation of photoswitchable 3D crystals with unique photoreversible growth and light-gated fluorescence [3]. Finally, I will present different colloidal self-assembly processes at air-water or liquid-liquid interfaces and explore how dynamic properties can emerge from such systems. Starting from the familiar situation of drying drop containing a colloidal suspensions, we have been interested in controlling\/cancelling the so-called \u201ccoffee-ring effect\u201d [4-7] or turning it into a low-cost yet powerful medical diagnostic tool [8]. In such systems, however, particles adsorb at the interface to form amorphous structures. This led us to invent a simple method in which bulk particles adsorb at the water-interface and directly crystallize there. Based on the use of ultralow amounts of surfactant, 2D colloidal crystals spontaneously form without any other applied force than their own weight [9]. This method allows us to crystallize a broad variety of nanometric and micrometric particles, including those made of polymers, metals or inorganic materials, and tune the characteristics of the colloidal crystals [10]. These colloidal crystals display intense structural colors as well as, under some conditions, some remarkable dynamic properties at the air\/water interface. For instance, using light, we can reversibly melt\/crystallize these colloidal assemblies on command, evidencing interesting life-like properties, such as dissipative or living crystallization [11,12].<\/p>\n

References:<\/b>
[1] Rossi-Gendron et al., ChemRxiv <\/i>2022 <\/b>(preprint), doi :\u00a0 10.26434\/chemrxiv-2022-12jqs
[2] Nakazawa et al., Angew. Chem. Int. Ed.<\/i> 2021<\/b>, 60, 15214 \u201315219
[3] Zhou et al., J. Am. Chem. Soc.<\/i> 2019<\/b>, 141, 9321\u20139329
[4] Anyfantakis et al., Angew. Chem. Int. Ed.<\/i> 2014<\/b>, 53, 14077\u201314081
[5] Varanakkottu et al., Nano Lett.<\/i> 2016<\/b>, 16, 644\u2013650
[6] Poulichet et al., J. Colloid. Interf. Sci.<\/i> 2020<\/b>, 573, 370-375
[7] Galy et al., ACS Appl. Mater. Interfaces<\/i> 2022<\/b>, 14, 3374\u20133384
[8] Devineau et al., J. Am. Chem. Soc. <\/i>2016<\/b>, 138, 11623\u201311632
[9] Anyfantakis, Langmuir<\/i> 2018<\/b>, 34, 15526\u221215536
[10] Vialetto et al., Nanoscale<\/i> 2020<\/b>, 12, 6279-6284
[11] Vialetto et al. Angew. Chem. Int. Ed.<\/i> 2019<\/b>, 58, 9145-9149
[12] Vialetto et al., J. Am. Chem. Soc.<\/i> 2021<\/b>, 143, 11535\u221211543<\/p>\n

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